Explain The Sliding Filament Theory

Definition

According to the sliding filament theory, musculus contraction occurs through the relative sliding of ii sets of filaments (actin and myosin). This sliding is produced by cyclic interactions of sidepieces from the myosin filament (cantankerous-bridges) with specific sites on the actin filament. Each such interaction is associated with a cantankerous-bridge power stroke whose energy is derived from the hydrolysis of adenosinetriphosphate (ATP), one ATP per cross-bridge bike.

Characteristics

Prior to the 1950s, muscle contraction and force production was associated with the shortening of myosin filaments. Myosin filaments can be seen with microscopy as the dark bands (the so chosen A-bands) in the striation pattern typical for skeletal and cardiac musculus (Fig. 1).

Sliding Filament Theory. Figure ane

Micrograph of a series of sarcomeres from an unmarried myofibril (top panel), an isolated sarcomere bordered past the z-lines and containing myosin (or thick filaments) in the A-band region and actin...

References

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Author data

Authors and Affiliations

1. Faculty of Kinesiology, University of Calgary, Calgary, Canada

   Walter Herzog

Editor information

Editors and Affiliations

1. Department of Physiology & Biophysics, Academy of Washington Schoolhouse of Medicine, Seattle, Washington, U.s.a.

   Marc D. Binder

2. Department of Cell Biological science and Beefcake, Graduate School of Medicine University of Tokyo Hongo, Bunkyo‐ku, Tokyo, Japan

   Nobutaka Hirokawa

3. Göttingen, Deutschland

   Uwe Windhorst

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© 2009 Springer-Verlag GmbH Berlin Heidelberg

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Herzog, West. (2009). Sliding Filament Theory. In: Binder, M.D., Hirokawa, North., Windhorst, U. (eds) Encyclopedia of Neuroscience. Springer, Berlin, Heidelberg. https://doi.org/x.1007/978-three-540-29678-2_5463

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Explain The Sliding Filament Theory,

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